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Article

DNA methylation as a diagnostic tool.

Acta neuropathologica communications - 8 May 2022

Galbraith Kristyn, Snuderl Matija

Abstract excerpt

DNA methylation of cytosines in CpG sites throughout the genome is an epigenetic mark contributing to gene expression regulation. DNA methylation patterns are specific to tissue type, conserved throughout life and reflect changes during tumorigenesis. DNA methylation recently emerged as a diagnostic tool to classify tumors based on a combination of preserved developmental and mutation induced signatures. In...

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Share to DNA Copy Number Variations
Share to DNA Methylation
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair Enzymes

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Source

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Identifiers

PMID: 35527288
DOI: 10.1186/s40478-022-01371-2
PMCID: PMC9080136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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