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Clinical Performance of Triage Strategies for Hr-HPV-Positive Women; A Longitudinal Evaluation of Cytology, p16/K-67 Dual Stain Cytology, and HPV16/18 Genotyping.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2022

Stanczuk Grazyna, Currie Heather, Forson William, Baxter Gwendoline, Lawrence James, Wilson Allan, Palmer Timothy, Arbyn Marc, Cuschieri Kate

Abstract excerpt

BACKGROUND: We evaluated the longitudinal performance of three options: HPV16/18 genotyping (HPV16/18), cytology (LBC), and p16/Ki-67 dual stain cytology (DS) for the triage of high-risk Human Papillomavirus-positive (Hr-HPV+) women within the cervical screening program in Scotland. METHODS: Data were derived from a cohort of Hr-HPV+ women (n = 385) who participated in PaVDaG (Papillomavirus Dumfries and...

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PMID: 35511738
DOI: 10.1158/1055-9965.EPI-21-1425

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