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Article

Whole genome sequencing to characterize the molecular epidemiology and drug-resistance of tuberculosis in Huzhou, China.

BMC genomics - 7 Nov 2025

Ji Lei, Ren Feilin, Xu Deshun, Zhu Xiaohua, Tong Zhaowei, Shen Jianyong, Zhang Peng

Abstract excerpt

BACKGROUND: Whole-genome sequencing (WGS) has emerged as a powerful tool for elucidating Mycobacterium tuberculosis (MTB) transmission dynamics and drug resistance patterns. In China, the application of WGS in TB surveillance has been rapidly expanding. However, molecular epidemiological studies based on WGS data from low-incidence areas remain limited. Huzhou City, located in northern Zhejiang Province, reported...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41204231
DOI: 10.1186/s12864-025-12202-8
PMCID: PMC12595642

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