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Hypoxia inducible lncRNA-CBSLR modulates ferroptosis through m6A-YTHDF2-dependent modulation of CBS in gastric cancer

6 Oct 2021

Abstract excerpt

Tumors are usually refractory to anti-cancer therapeutics under hypoxic conditions. However, the underlying molecular mechanism remains to be elucidated. Our study intended to identify hypoxia inducible lncRNAs and their biological function in gastric cancer (GC). Differentially expressed lncRNAs were determined by microarray analysis between GC cells exposed to hypoxia (1% O2) and normoxia (21% O2) for 24 h. The...

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PMID: 35499052
DOI: 10.1016/j.jare.2021.10.001

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