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Article

In vitro activity of letermovir against human cytomegalovirus isolates with different drug susceptibility phenotypes.

Antiviral research - 1 Jun 2022

Piret Jocelyne, Goyette Nathalie, Boivin Guy

Abstract excerpt

Letermovir (LTV) is approved for the prophylaxis of human cytomegalovirus (HCMV) infection in adult seropositive recipients of an allogeneic hematopoietic stem cell transplant. Here, we report on the in vitro activity of LTV against a large panel of clinical HCMV isolates and recombinant viruses with different drug susceptibility phenotypes to currently-approved DNA polymerase inhibitors or maribavir. No...

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Identifiers

PMID: 35490740
DOI: 10.1016/j.antiviral.2022.105328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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