Article
Immunosuppressants contribute to a reduced risk of Parkinson's disease in rheumatoid arthritis.
International journal of epidemiology - 10 Aug 2022
Guo Xingzhi, Chong Li, Zhang Xin, Li Rui
Abstract excerpt
BACKGROUND: Observational studies have suggested a decreased risk of Parkinson's disease (PD) in patients with rheumatoid arthritis (RA). However, the results are controversial and the biological mechanism underlying this effect remains largely unknown. METHODS: The effect sizes of five observational studies were summarized to determine the association between RA and PD. A two-step Mendelian randomization (TSMR)...
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