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Faster Cryptococcus Melanization Increases Virulence in Experimental and Human Cryptococcosis

12 Apr 2022

Abstract excerpt

Cryptococcus spp. are human pathogens that cause 181,000 deaths per year. In this work, we systematically investigated the virulence attributes of Cryptococcus spp. clinical isolates and correlated them with patient data to better understand cryptococcosis. We collected 66 C. neoformans and 19 C. gattii clinical isolates and analyzed multiple virulence phenotypes and host–pathogen interaction outcomes. C....

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PMID: 35448624
DOI: 10.3390/jof8040393

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