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Article

Strain-specific variation in virulence and host-immune modulation across the Cryptococcus gattii species complex.

International journal of medical microbiology : IJMM - 1 Jun 2026

Bellet Virginie, Brochon Léo, Chable de la Héronnière François, Krasteva Donika, Boudard Frédéric, Roger Frédéric, Drakulovski Pascale, Bertout Sébastien

Abstract excerpt

Cryptococcus gattii is an environmental yeast capable of causing severe infections in immunocompetent hosts. Its virulence mechanisms remain less characterized than those of C. neoformans. This study aimed to evaluate the expression of major virulence factors and the immunomodulatory potential of eight C. gattii strains representing five genotypes and multiple sequence types (STs). Virulence traits-including...

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Identifiers

PMID: 41759398
DOI: 10.1016/j.ijmm.2026.151708

Genes

ST7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

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