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Article

Targeting cellular senescence as a novel treatment for osteoarthritis.

Current opinion in pharmacology - 1 Jun 2022

Astrike-Davis Emma M, Coryell Philip, Loeser Richard F

Abstract excerpt

Cellular senescence is associated with normal development and wound healing, but has also been implicated in the pathogenesis of numerous aging-related diseases including osteoarthritis (OA). Treatment strategies for OA are being developed that target senescent cells and the paracrine and autocrine secretions of the senescence-associated secretory phenotype (SASP). The field of potential therapies continues to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35447516
DOI: 10.1016/j.coph.2022.102213
PMCID: PMC9167736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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