Article
Clinical outcomes of EGFR+/METamp+ vs. EGFR+/METamp- untreated patients with advanced non-small cell lung cancer.
Thoracic cancer - 1 Jun 2022
Peng Kai-Cheng, Su Jun-Wei, Xie Zhi, Wang Han-Min, Fang Mei-Mei, Li Wen-Feng, Chen Yu-Qing, Guan Xu-Hui, Su Jian, Yan Hong-Hong, Zhang Xu-Chao, Tu Hai-Yan, Zhou Qing, Chen Hua-Jun, Wu Yi-Long, Yang Jin-Ji
Abstract excerpt
BACKGROUND: MET dysregulation has been implicated in the development of primary and secondary resistance to EGFR tyrosine kinase inhibitor (TKI) therapy. However, the clinicopathological characteristics and outcomes of patients harboring EGFR-sensitive mutations and de novo MET amplifications still need to be explored. METHODS: A total of 54 patients from our hospital with non-small cell lung cancer harboring...
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