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Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span

15 Apr 2022

Abstract excerpt

Changes in the proteome of different human tissues with advancing age are poorly characterized. Here, we studied the proteins present in primary skin fibroblasts collected from 82 healthy individuals across a wide age spectrum (22-89 years old) who participated in the GESTALT (Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing) study of the National Institute on Aging, NIH. Proteins were...

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PMID: 35429111
DOI: 10.1111/acel.13609

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