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Article

Circulating miR-499a-5p Is a Potential Biomarker of MYH7-Associated Hypertrophic Cardiomyopathy.

International journal of molecular sciences - 30 Mar 2022

Baulina Natalia, Pisklova Maria, Kiselev Ivan, Chumakova Olga, Zateyshchikov Dmitry, Favorova Olga

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is the most common inherited myocardial disease with significant genetic and phenotypic heterogeneity. To search for novel biomarkers, which could increase the accuracy of HCM diagnosis and improve understanding of its phenotype formation, we analyzed the levels of circulating miRNAs—stable non-coding RNAs involved in post-transcriptional gene regulation. Performed high...

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Identifiers

PMID: 35409153
DOI: 10.3390/ijms23073791
PMCID: PMC8998764

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