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[The GG genotype of the HSPA1B gene is associated with increased risk of glaucoma in northern Iran].

Molekuliarnaia biologiia - 1 Jan 2000

Salehi Z, Gholaminia M, Gholaminia Z, Panjtanpanah M, Qazvini M G

Abstract excerpt

Glaucoma is a heterogeneous eye disease characterized by optic nerve atrophy and visual field defects. The disease damages the retinal ganglion cells (RGC) and their functional axons. Heat shock proteins 70 (HSP70) are molecular chaperons that could have a protective effect in the development of glaucoma. Polymorphisms of HSP70 may alter protein function or expression and are associated with the susceptibility to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28251963
DOI: 10.7868/S0026898416060185

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