Article
Key historical study findings questioned in debate over threshold versus linear non-threshold for cancer risk assessment.
Chemico-biological interactions - 25 May 2022
Calabrese Edward J
Abstract excerpt
This paper demonstrates that the dissertation research of Ray-Chaudhuri (1939, 1944) that was used by Hermann Muller to support his radiation induced gene mutation hypothesis and linear non-threshold (LNT) dose response model during his Nobel Prize Lecture is "uninterpretable" with respect to these issues. The research failed to include essential research design information, resulting in reporting flaws that have...
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