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The threshold vs LNT showdown: Dose rate findings exposed flaws in the LNT model part 1. The Russell-Muller debate.

Environmental research - 1 Apr 2017

Calabrese Edward J

Abstract excerpt

This paper assesses the discovery of the dose-rate effect in radiation genetics and how it challenged fundamental tenets of the linear non-threshold (LNT) dose response model, including the assumptions that all mutational damage is cumulative and irreversible and that the dose-response is linear at low doses. Newly uncovered historical information also describes how a key 1964 report by the International...

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Identifiers

PMID: 28109526
DOI: 10.1016/j.envres.2016.12.006

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