Establishment of Immortalized Yak Ruminal Epithelial Cell Lines by Lentivirus‐Mediated SV40T and hTERT Gene Transduction

Abstract excerpt

Yak is a unique species of cattle that is adapted to the harsh natural environment of the Qinghai-Tibet Plateau. Research on the function of the yak rumen is limited to animal experiments, and the cell molecular mechanism is very limited. The high cost of isolation and culture of adult yak rumen epithelial cells (YRECs), low success rate, and limited cell life limit the scope of long-term physiological functions...

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