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Serum proteomics links suppression of tumor immunity to ancestry and lethal prostate cancer

1 Apr 2022

Abstract excerpt

There is evidence that tumor immunobiology and immunotherapy response may differ between African American and European American prostate cancer patients. Here, we determine if men of African descent harbor a unique systemic immune-oncological signature and measure 82 circulating proteins in almost 3000 Ghanaian, African American, and European American men. Protein signatures for suppression of tumor immunity and...

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PMID: 35365620
DOI: 10.1038/s41467-022-29235-2

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