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Article

PPARα polymorphisms association with total cholesterol and LDL-C levels in a Mexican population.

European review for medical and pharmacological sciences - 1 Mar 2022

Ortega-Meléndez A I, Montero-Molina S, Jiménez-Ortega R F, Ramírez-López E, Campos-Góngora E, Velázquez-Cruz R, Jiménez-Salas Z, Balderas-Rentería I

Abstract excerpt

OBJECTIVE: Peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear transcription factor with a role in gene expression changes associated to lipid metabolism. PPARα polymorphic variants have been previously correlated to serum lipid profile but in Mexico, there is no previous report about that association. For this reason, the aim of this study was to investigate the relationship between PPARα...

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PMID: 35363365
DOI: 10.26355/eurrev_202203_28363

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