Article
Association of PPARalpha gene polymorphisms and lipid serum levels in a Brazilian elderly population.
Experimental and molecular pathology - 1 Feb 2010
Chen Elizabeth Suchi, Mazzotti Diego Robles, Furuya Tatiane Katsue, Cendoroglo Maysa Seabra, Ramos Luiz Roberto, Araujo Lara Quirino, Burbano Rommel Rodriguez, Smith Marília de Arruda Cardoso
Abstract excerpt
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear transcription factor strictly involved in lipid and lipoprotein metabolisms. Thus, PPARalpha gene polymorphisms have been investigated as cardiovascular risk factors. We aimed to investigate associations of L162V and intron 7G>C polymorphisms with common morbidities affecting a Brazilian elderly cohort as well as with lipid and protein...
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