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Article

NeuroSCORE is a genome-wide omics-based model that identifies candidate disease genes of the central nervous system.

Scientific reports - 31 Mar 2022

Davis Kyle W, Bilancia Colleen G, Martin Megan, Vanzo Rena, Rimmasch Megan, Hom Yolanda, Uddin Mohammed, Serrano Moises A

Abstract excerpt

To identify candidate disease genes of central nervous system (CNS) phenotypes, we created the Neurogenetic Systematic Correlation of Omics-Related Evidence (NeuroSCORE). We identified five genome-wide metrics highly associated with CNS phenotypes to score 19,601 protein-coding genes. Genes scored one point per metric (range: 0-5), identifying 8298 scored genes (scores ≥ 1) and 1601 "high scoring" genes...

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Identifiers

PMID: 35361823
DOI: 10.1038/s41598-022-08938-y
PMCID: PMC8971396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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