Article
Cardiac events in patients with acute myeloid leukemia treated with venetoclax combined with hypomethylating agents
1 Apr 2022
Abstract excerpt
Venetoclax, a small-molecule inhibitor of B-cell lymphoma-2, in combination with the hypomethylating agents (HMA) azacitidine or decitabine, is FDA-approved for elderly/unfit patients with acute myeloid leukemia (AML). It is frequently used both in the upfront and relapsed/refractory setting based on superior efficacy and improved survival of the combination regimen compared with HMA alone.
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