Article
Venetoclax and hypomethylating agents in acute myeloid leukemia: Mayo Clinic series on 86 patients.
American journal of hematology - 1 Dec 2020
Morsia Erika, McCullough Kristen, Joshi Maansi, Cook Joselle, Alkhateeb Hassan B, Al-Kali Aref, Begna Kebede, Elliott Michelle, Hogan William, Litzow Mark, Shah Mithun, Pardanani Animesh, Patnaik Mrinal, Tefferi Ayalew, Gangat Naseema
Abstract excerpt
Venetoclax and hypomethylating agent (HMA) combination therapy is FDA-approved for elderly or unfit acute myeloid leukemia (AML) patients unable to withstand intensive chemotherapy. The primary objective of the current study was to impart our institutional experience with the above regimen, outlining response, survival outcomes, and its determinants amongst 86 treatment- naïve and relapsed/refractory AML...
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