Article
A genome-wide association study of suicide attempts in the million veterans program identifies evidence of pan-ancestry and ancestry-specific risk loci.
Molecular psychiatry - 1 Apr 2022
Kimbrel Nathan A, Ashley-Koch Allison E, Qin Xue J, Lindquist Jennifer H, Garrett Melanie E, Dennis Michelle F, Hair Lauren P, Huffman Jennifer E, Jacobson Daniel A, Madduri Ravi K, Trafton Jodie A, Coon Hilary, Docherty Anna R, Kang Jooeun, Mullins Niamh, Ruderfer Douglas M, Harvey Philip D, McMahon Benjamin H, Oslin David W, Hauser Elizabeth R, Hauser Michael A, Beckham Jean C
Abstract excerpt
To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among veterans, we conducted a genome-wide association study (GWAS) of suicide attempts within a large, multi-ancestry cohort of U.S. veterans enrolled in the Million Veterans Program (MVP). Cases were defined as veterans with a documented history of suicide attempts in the electronic health record (EHR; N = 14,089) and...
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