Practical tips for managing FLT3 mutated acute myeloid leukemia with midostaurin.

doi:10.1080/17474086.2022.2054801

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Article

Practical tips for managing FLT3 mutated acute myeloid leukemia with midostaurin.

Expert review of hematology - 1 Mar 2022

Arnán Sangerman Montserrat, Fernández Moreno Ainhoa, García Quintana Antonio, García-Vidal Carolina, Olave Rubio María Teresa, Del Mar Tormo Díaz María, Vendranas Meritxell, Rodriguez Macias Gabriela

Abstract excerpt

INTRODUCTION: FLT3 inhibitors have been recently introduced as novel treatment targets in patients with FLT3-mutated acute myeloid leukemia (AML). Midostaurin is an oral multikinase inhibitor that targets multiple receptor tyrosine kinases including FLT3 and has been approved for the treatment of...

Topics

Antifungal Agents
Antineoplastic Agents
Humans
Leukemia, Myeloid, Acute
Mutation
Protein Kinase Inhibitors
Staurosporine
fms-Like Tyrosine Kinase 3

Source

Open in PubMed

Identifiers

PMID: 35332831
DOI: 10.1080/17474086.2022.2054801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-35332831-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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