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Article

HNF1A Mutations and Beta Cell Dysfunction in Diabetes.

International journal of molecular sciences - 16 Mar 2022

Miyachi Yasutaka, Miyazawa Takashi, Ogawa Yoshihiro

Abstract excerpt

Understanding the genetic factors of diabetes is essential for addressing the global increase in type 2 diabetes. HNF1A mutations cause a monogenic form of diabetes called maturity-onset diabetes of the young (MODY), and HNF1A single-nucleotide polymorphisms are associated with the development of type 2 diabetes. Numerous studies have been conducted, mainly using genetically modified mice, to explore the...

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Share to Pancreatic function and diabetes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35328643
DOI: 10.3390/ijms23063222
PMCID: PMC8948720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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