Article
Role of altered IL-33/ST2 immune axis in the immunobiology of Guillain-Barré syndrome.
European journal of neurology - 1 Jul 2022
Sharma Praveen P, Seshagiri Doniparthi V, Nagappa Madhu, Mullapudi Thrinath, Sreenivas Nikhitha, Dey Saikat, Shivaram Sumanth, Wahatule Rahul, Kumawat Vijay, Sreekumaran Nair Binu V, Kamath Sriganesh, Sinha Sanjib, Taly Arun B, Debnath Monojit
Abstract excerpt
BACKGROUND: The IL-33/ST2 immune axis plays crucial roles in infection and immunity. A dysregulated IL-33/ST2 axis can induce autoimmune reaction and inflammatory responses. Guillain-Barré syndrome (GBS) is an acute peripheral neuropathy, mostly caused by post-infection autoimmunity. The role of IL-33/ST2 axis is not known in GBS. This study aimed to explore the role of IL-33/ST2 axis in GBS. METHODS: Three...
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