Article
Key pituitary miRNAs mediate the expression of pig GHRHR splice variants by regulating splice factors.
International journal of biological macromolecules - 31 May 2022
Teng Zhaohui, Hao Linlin, Yang Rui, Song Jie, Wang Zhaoguo, Jiao Yingying, Fang Jiayuan, Zheng Shuo, Ma Ze, Chen Xi, Liu Songcai, Cheng Yunyun
Abstract excerpt
The growth hormone releasing hormone receptor (GHRHR) is well documented in organism growth and its alternative splicing may generate multiple functional GHRHR splice variants (SVs). Our previous study has demonstrated the key pituitary miRNAs (let-7e and miR-328-5p) in pig regulated the expression of GHRHR SVs by directly targeting to them. And according to recent reports, the interplay between miRNA-based...
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