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Article

DTL promotes melanoma progression through rewiring cell glucose metabolism

1 Jan 2022

Abstract excerpt

Background: To investigate the role of DTL in the development of skin cutaneous melanoma (SKCM) and possible mechanisms. Methods: We examined the expression of DTL in SKCM in The Cancer Genome Atlas (TCGA) and Oncomine database and analyzed the relationship between DTL expression and melanoma prognosis. Furthermore, we silenced the DTL gene by RNA interference in A375 cells and investigated the effect of DTL...

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PMID: 35282044
DOI: 10.21037/atm-21-6648

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