Article
Artificial Intelligence Program to Predict p53 Mutations in Ulcerative Colitis-Associated Cancer or Dysplasia.
Inflammatory bowel diseases - 1 Jul 2022
Noguchi Tatsuki, Ando Takumi, Emoto Shigenobu, Nozawa Hiroaki, Kawai Kazushige, Sasaki Kazuhito, Murono Koji, Kishikawa Junko, Ishi Hiroaki, Yokoyama Yuichiro, Abe Shinya, Nagai Yuzo, Anzai Hiroyuki, Sonoda Hirofumi, Hata Keisuke, Sasaki Takeshi, Ishihara Soichiro
Abstract excerpt
BACKGROUND: The diagnosis of colitis-associated cancer or dysplasia is important in the treatment of ulcerative colitis. Immunohistochemistry of p53 along with hematoxylin and eosin (H&E) staining is conventionally used to accurately diagnose the pathological conditions. However, evaluation of p53 immunohistochemistry in all biopsied specimens is expensive and time-consuming for pathologists. In this study, we...
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