Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3+ and CD8+ T cell density and predict prognosis in hepatocellular carcinoma

1 Mar 2022

Abstract excerpt

Background Hepatocellular carcinoma (HCC) is a highly lethal cancer and the second leading cause of cancer-related deaths worldwide. As demonstrated in other solid neoplasms and HCC, infiltrating CD8+ T cells seem to be related to a better prognosis, but the mechanisms affecting the immune landscape in HCC are still mostly unknown. Necroptosis is a programmed, caspase-independent cell death that, unlike...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to Ferroptosis and cancer prognosis
Share to Phagocytosis and Immune Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35264437
DOI: 10.1136/jitc-2021-004031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3+ and CD8+ T cell density and predict prognosis in hepatocellular carcinomaPMID 35264437Read ↗

Necrosis-associated long noncoding RNA for predicting prognosis in hepatocellular carcinomaSemantic proximity Read ↗

A necroptosis‐related gene signature for predicting prognosis, immune landscape, and drug sensitivity in hepatocellular carcinomaSemantic proximity Read ↗

A Necroptosis-Related Gene Signature for Predicting Prognosis, Immune Landscape, and Therapy Sensitivity in Hepatocellular CarcinomaSemantic proximity Read ↗

Construction of a Necroptosis-Associated Long Non-Coding RNA Signature to Predict Prognosis and Immune Response in Hepatocellular CarcinomaSemantic proximity Read ↗

Construction and Validation of a Necroptosis-Related Signature Associated With the Immune Microenvironment in Liver Hepatocellular CarcinomaSemantic proximity Read ↗

Developing a signature based on necroptosis-related lncRNAs to predict the prognosis and immunotherapy response of hepatocellular carcinomaSemantic proximity Read ↗

Identification and validation of a five-necroptosis-related lncRNAs signature for prognostic prediction in hepatocellular carcinomaSemantic proximity Read ↗

The role of necroptosis in cancer biology and therapySemantic proximity Read ↗

Construction of a Ferroptosis and Necroptosis Associated LncRNA Signature for Predicting Prognosis and Immunotherapy Response in Hepatocellular cancerSemantic proximity Read ↗

Machine learning-based construction of a ferroptosis and necroptosis associated lncRNA signature for predicting prognosis and immunotherapy response in hepatocellular cancerSemantic proximity Read ↗

The Pyroptosis-Related Gene Signature Predicts the Prognosis of Hepatocellular CarcinomaSemantic proximity Read ↗

A Pyroptosis-Related Gene Signature to Predict Patients' Prognosis and Immune Landscape in Liver Hepatocellular Carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.