A Pyroptosis-Related Gene Signature to Predict Patients' Prognosis and Immune Landscape in Liver Hepatocellular Carcinoma.

doi:10.1155/2022/1258480

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Article

A Pyroptosis-Related Gene Signature to Predict Patients' Prognosis and Immune Landscape in Liver Hepatocellular Carcinoma.

Computational and mathematical methods in medicine - 1 Jan 2022

Wang Jiakun, Huang Zhihao, Lu Hongcheng, Zhang Rongguiyi, Feng Qian, He Aoxiao

Abstract excerpt

BACKGROUND: Liver hepatocellular carcinoma (LIHC) is a malignance with high incidence and recurrence. Pyroptosis is a programed cell death pattern which both activates the effective immune response and causes cell damage. However, their potential applications of pyroptosis-related genes (PRGs) in the prognostic evaluation and immunotherapy of LIHC are still rarely discussed. METHODS: Comprehensive bioinformatics...

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PMID: 35242200
DOI: 10.1155/2022/1258480
PMCID: PMC8886769

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