Article
Longitudinal Impact of Sputum Inflammatory Phenotypes on Small Airway Dysfunction and Disease Outcomes in Asthma.
The journal of allergy and clinical immunology. In practice - 1 Jun 2022
Abdo Mustafa, Pedersen Frauke, Kirsten Anne-Marie, Veith Vera, Biller Heike, Trinkmann Frederik, von Mutius Erika, Kopp Matthias, Hansen Gesine, Rabe Klaus F, Bahmer Thomas, Watz Henrik
Abstract excerpt
BACKGROUND: Little is known about the relationship between airway inflammatory phenotypes and some important asthma features such as small airway dysfunction (SAD). OBJECTIVE: To describe the longitudinal impact of airway inflammatory phenotypes on SAD and asthma outcomes. METHODS: We measured eosinophil and neutrophil counts in induced sputum at baseline and 1 year later to stratify 197 adult patients with...
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