Article
Sputum inflammatory phenotypes are not stable in children with asthma.
Thorax - 1 Aug 2012
Fleming Louise, Tsartsali Lemonia, Wilson Nicola, Regamey Nicolas, Bush Andrew
Abstract excerpt
BACKGROUND: Two distinct, stable inflammatory phenotypes have been described in adults with asthma: eosinophilic and non-eosinophilic. Treatment strategies based on these phenotypes have been successful. This study evaluated sputum cytology in children with asthma to classify sputum inflammatory phenotypes and to assess their stability over time. METHODS: Sputum induction was performed in 51 children with severe...
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