Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A highly immunogenic live-attenuated vaccine candidate prevents SARS-CoV-2 infection and transmission in hamsters

1 Mar 2022

Abstract excerpt

The highly pathogenic and readily transmissible SARS-CoV-2 has caused a global coronavirus pandemic, urgently requiring effective countermeasures against its rapid expansion. All available vaccine platforms are being used to generate safe and effective COVID-19 vaccines. Here, we generated a live-attenuated candidate vaccine strain by serial passaging of a SARS-CoV-2 clinical isolate in Vero cells. Deep...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35252935
DOI: 10.1016/j.xinn.2022.100221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A highly immunogenic live-attenuated vaccine candidate prevents SARS-CoV-2 infection and transmission in hamstersPMID 35252935Read ↗

Covid-19: virology, variants, and vaccinesSemantic proximity Read ↗

A Comprehensive Review on the Current Vaccines and Their Efficacies to Combat SARS-CoV-2 VariantsSemantic proximity Read ↗

SARS-CoV-2–Specific Vaccine Candidates; the Contribution of Structural VaccinologySemantic proximity Read ↗

The success of SARS-CoV-2 vaccines and challenges ahead.Semantic proximity Read ↗

Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.Semantic proximity Read ↗

Synthetic Multiantigen MVA Vaccine COH04S1 Protects Against SARS-CoV-2 in Syrian Hamsters and Non-Human PrimatesSemantic proximity Read ↗

Efficacy of parainfluenza virus 5 (PIV5)-vectored intranasal COVID-19 vaccine as a single dose primer and booster against SARS-CoV-2 variantsSemantic proximity Read ↗

A T cell-targeted multi-antigen vaccine generates robust cellular and humoral immunity against SARS-CoV-2 infectionSemantic proximity Read ↗

Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidatesSemantic proximity Read ↗

Pathogenicity, immunogenicity, and protective ability of an attenuated SARS-CoV-2 variant with a deletion at the S1/S2 junction of the spike proteinSemantic proximity Read ↗

The Cold-Adapted, Temperature-Sensitive SARS-CoV-2 Strain TS11 Is Attenuated in Syrian Hamsters and a Candidate Attenuated VaccineSemantic proximity Read ↗

Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.