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SARS-CoV-2–Specific Vaccine Candidates; the Contribution of Structural Vaccinology

3 Feb 2022

Abstract excerpt

SARS-CoV-2 vaccine production has taken us by storm. We aim to fill in the history of concepts and the work of pioneers and provide a framework of strategies employing structural vaccinology. Cryo-electron microscopy became crucial in providing three-dimensional (3D) structures and creating candidates eliciting T and B cell-mediated immunity. It also determined structural changes in the emerging mutants in order...

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PMID: 35214693
DOI: 10.3390/vaccines10020236

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