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Article

Pathologist initiated reflex BRAF mutation testing in metastatic melanoma: experience at a specialist melanoma treatment centre.

Pathology - 1 Aug 2022

Potter Alison J, Colebatch Andrew J, Rawson Robert V, Ferguson Peter M, Cooper Wendy A, Gupta Ruta, O'Toole Sandra, Saw Robyn P M, Ch'ng Sydney, Menzies Alexander M, Long Georgina V, Scolyer Richard A

Abstract excerpt

Testing for BRAF mutations in metastatic melanoma is pivotal to identifying patients suitable for targeted therapy and influences treatment decisions regarding single agent versus combination immunotherapy. Knowledge of BRAF V600E immunohistochemistry (IHC) results can streamline decisions during initial oncology consultations, prior to DNA-based test results. In the absence of formal guidelines that require...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35249747
DOI: 10.1016/j.pathol.2021.12.290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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