Article
Mutational status may supersede tumor size in predicting the presence of aggressive pathologic features in well differentiated thyroid cancer.
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale - 4 Mar 2022
Semsar-Kazerooni Koorosh, Morand Grégoire B, Payne Alexandra E, da Silva Sabrina D, Forest Véronique-Isabelle, Hier Michael P, Pusztaszeri Marc P, Tamilia Michael, Payne Richard J
Abstract excerpt
BACKGROUND: In clinical practice, thyroid tumor size plays a critical role in the staging of thyroid malignancies and in the selection of nodules that should undergo ultrasound-guided fine-needle aspiration. Thyroid tumor size is influenced by the elapsed time since the beginning of oncogenesis and by the presence of somatic mutations driving growth, such as BRAFV600E mutations, associated with aggressive...
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