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Perfect match: mTOR inhibitors and tuberous sclerosis complex

4 Mar 2022

Abstract excerpt

Tuberous sclerosis complex (TSC) is an autosomal dominant syndrome that presents with diverse and complex clinical features and involves multiple human systems. TSC-related neurological abnormalities and organ dysfunction greatly affect the quality of life and can even result in death in patients with TSC. It is widely accepted that most TSC-related clinical manifestations are associated with hyperactivation of...

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PMID: 35246210
DOI: 10.1186/s13023-022-02266-0

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