Article
Whole-genome sequencing of Chlamydia trachomatis isolates from persistently infected patients.
International journal of STD & AIDS - 1 Apr 2022
Pitt Rachel, Doyle Ronan, Theilgaard Christiansen Mette, Horner Paddy, Hathorn Emma, Alexander Sarah, Woodford Neil, Cole Michelle, Breuer Judith
Abstract excerpt
BACKGROUND: Current understanding of the causes of treatment failure in Chlamydia trachomatis is poor and antimicrobial susceptibility data are lacking. We used genome sequencing to seek evidence of antimicrobial resistance in isolates sourced from patients who were persistently infected. METHODS: Genomic DNA was extracted from C. trachomatis isolates cultured in McCoy cell monolayers. Sequencing libraries were...
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