Article
Whole‐exome sequencing uncovers new variants in GDF15 associated with hyperemesis gravidarum
26 Feb 2022
Abstract excerpt
Abstract Objective A genome‐wide association study (GWAS) linked the placenta and appetite hormone gene GDF15 to hyperemesis gravidarum (HG). This paradigm‐changing finding has shifted the field away from the prevailing hypotheses, but more evidence is needed. This study was performed to identify coding variants in addition to the non‐coding variants implicated by GWAS. Setting Case–control research study...
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