Article
Clinical and radiographic characteristics of diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma: a single institution review.
Journal of neuro-oncology - 1 Mar 2022
Grogan Dayton, Bray David P, Cosgrove Megan, Boucher Andrew, Erwood Andrew, Linder Daniel F, Mendoza Pia, Morales Bryan, Pradilla Gustavo, Nduom Edjah K, Neill Stewart, Olson Jeffrey J, Hoang Kimberly B
Abstract excerpt
PURPOSE: Genetic analyses of gliomas have identified key molecular features that impact treatment paradigms beyond conventional histomorphology. Despite at-times lower grade histopathologic appearances, IDH-wildtype infiltrating gliomas expressing certain molecular markers behave like higher-grade tumors. For IDH-wildtype infiltrating gliomas lacking traditional features of glioblastoma, these markers form the...
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