Article
Pneumococcal meningitis in adults in 2014-2018 after introduction of pediatric 13-valent pneumococcal conjugate vaccine in Japan.
Scientific reports - 23 Feb 2022
Chang Bin, Tamura Kosuke, Fujikura Hiroyuki, Watanabe Hiroshi, Tanabe Yoshinari, Kuronuma Koji, Fujita Jiro, Oshima Kengo, Maruyama Takaya, Abe Shuichi, Kasahara Kei, Nishi Junichiro, Kubota Tetsuya, Kinjo Yuki, Serizawa Yusuke, Shimbashi Reiko, Fukusumi Munehisa, Shimada Tomoe, Sunagawa Tomimasa, Suzuki Motoi, Oishi Kazunori
Abstract excerpt
We assessed the impact of the pediatric 13-valent pneumococcal conjugate vaccine (PCV13) on pneumococcal meningitis in adults in Japan in 2014-2018 by comparing epidemiological characteristics of adults with invasive pneumococcal disease with (n = 222) and without (n = 1258) meningitis. The annual incidence of pneumococcal meningitis in 2016-2018 was 0.20-0.26 cases/100,000 population. Age (p < 0.001) and case...
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