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Japanese encephalitis genotype I virus-like particles stably expressed in BHK-21 cells serves as potential antigen in JE IgM ELISA.

Applied microbiology and biotechnology - 1 Mar 2022

Mali D N, Bondre V P

Abstract excerpt

Japanese encephalitis virus (JEV) is one of the leading causes of epidemic encephalitis in South Asian countries. Due to the short-term viremia, detecting IgM antibodies by ELISA is treated as the front-line diagnostic assay. Co-circulation and multiple exposures to antigenically cross-reactive flaviviruses in India pose a challenge in serodiagnosis. Replacing the whole virus antigen currently used in the JE IgM...

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Identifiers

PMID: 35175398
DOI: 10.1007/s00253-022-11825-1
PMCID: PMC8979883

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