Article
Case Report: Sarcoid-Like Reactions and Tertiary Lymphoid Structures Following Dual Checkpoint Inhibition in a Patient with Early-Stage Lung Adenocarcinoma.
Frontiers in immunology - 1 Jan 2022
Zhao Xiaoliang, Yue Dongsheng, Qian Juanjuan, Zhang Lei, Song Jin, Zhang Bin, Zhang Chunmei, Sun Leina, Ma Yuchen, Zhang Henghui, Wang Changli
Abstract excerpt
Immune checkpoint inhibitor-induced sarcoid-like reactions and tertiary lymphoid structures (TLSs) are increasingly recognized but rarely reported in the same patient. We report a patient with lung adenocarcinoma who displayed sarcoid-like reactions in intrathoracic lymph nodes and tertiary lymphoid structures in surgical tumor after neoadjuvant therapy with nivolumab plus ipilimumab. Pathological examination...
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