Genome-wide association study and functional follow-up identify 14q12 as a candidate risk locus for cervical cancer.

doi:10.1093/hmg/ddac031

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Genome-wide association study and functional follow-up identify 14q12 as a candidate risk locus for cervical cancer.

Human molecular genetics - 17 Aug 2022

Ramachandran Dhanya, Dennis Joe, Fachal Laura, Schürmann Peter, Bousset Kristine, Hülse Fabienne, Mao Qianqian, Wang Yingying, Jentschke Matthias, Böhmer Gerd, Strauß Hans-Georg, Hirchenhain Christine, Schmidmayr Monika, Müller Florian, Runnebaum Ingo, Hein Alexander, Stübs Frederik, Koch Martin, Ruebner Matthias, Beckmann Matthias W, Fasching Peter A, Luyten Alexander, Dürst Matthias, Hillemanns Peter, Easton Douglas F, Dörk Thilo

Abstract excerpt

Cervical cancer is among the leading causes of cancer-related death in females worldwide. Infection by human papillomavirus (HPV) is an established risk factor for cancer development. However, genetic factors contributing to disease risk remain largely unknown. We report on a genome-wide association study (GWAS) on 375 German cervical cancer patients and 866 healthy controls, followed by a replication study...

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PMID: 35157032
DOI: 10.1093/hmg/ddac031
PMCID: PMC9396939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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