Article
Mitogen Synergy: An Emerging Route to Boosting Human Beta Cell Proliferation
27 Jan 2022
Abstract excerpt
Decreased number and function of beta cells are a key aspect of diabetes mellitus (diabetes), a disease that remains an onerous global health problem. Means of restoring beta cell mass are urgently being sought as a potential cure for diabetes. Several strategies, such asde novobeta cell derivation via pluripotent stem cell differentiation or mature somatic cell transdifferentiation, have yielded promising...
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