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Article

Unsupervised cluster analysis and subset characterization of abnormal erythropoiesis using the bioinformatic <scp>Flow‐Self</scp> Organizing Maps algorithm

12 Feb 2022

Abstract excerpt

BACKGROUND: The Flow-Self Organizing Maps (FlowSOM) artificial intelligence (AI) program, available within the Bioconductor open-source R-project, allows for an unsupervised visualization and interpretation of multiparameter flow cytometry (MFC) data. METHODS: Applied to a reference merged file from 11 normal bone marrows (BM) analyzed with an MFC panel targeting erythropoiesis, FlowSOM allowed to identify six...

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PMID: 35150187
DOI: 10.1002/cyto.b.22059

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