Article
PhenoGraph and viSNE facilitate the identification of abnormal T-cell populations in routine clinical flow cytometric data.
Cytometry. Part B, Clinical cytometry - 1 Sept 2018
DiGiuseppe Joseph A, Cardinali Jolene L, Rezuke William N, Pe'er Dana
Abstract excerpt
BACKGROUND: Flow cytometric identification of neoplastic T-cell populations is complicated by the wide range of phenotypic abnormalities in T-cell neoplasia, and the diverse repertoire of reactive T-cell phenotypes. We evaluated whether a recently described clustering algorithm, PhenoGraph, and dimensionality-reduction algorithm, viSNE, might facilitate the identification of abnormal T-cell populations in routine...
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