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Definition of Erythroid Differentiation Subsets in Normal Human Bone Marrow Using FlowSOM Unsupervised Cluster Analysis of Flow Cytometry Data

21 Dec 2020

Abstract excerpt

Erythropoiesis is a complex process that ensures the production of about 200 billion erythrocytes every day, at a rate of almost 2 million per second in humans. Knowledge of the maturation process of red blood cells comes mostly from morphological analysis of bone marrow (BM) smears or biopsies, colony unit formation studies in cultures, and electron microscopy.1-3 Multiparameter flow cytometry (MFC) explorations...

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PMID: 33364551
DOI: 10.1097/hs9.0000000000000512

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