Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multi-omics data identified TP53 and LRP1B as key regulatory gene related to immune phenotypes via EPCAM in HCC.

Cancer medicine - 1 May 2022

Shi Liang, Cao Jie, Lei Xin, Shi Yifen, Wu Lili

Abstract excerpt

BACKGROUND: Many studies showed that the prognosis of hepatocellular carcinoma (HCC) was significantly associated with the expressions of TP53 and LRP1B. However, the potential influence of the two genes on the malignant progression of HCC is still to be expounded. METHODS: According to the correlation analysis between immune cells and expression levels of TP53 and LRP1B, we filtered the immune cells to perform...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cell Adhesion Molecule

Share to Gene Regulatory Networks

Share to Genes, Regulator

Share to Liver Neoplasms

Share to Receptors, LDL

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 35150083
DOI: 10.1002/cam4.4594
PMCID: PMC9119357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multi-omics data identified TP53 and LRP1B as key regulatory gene related to immune phenotypes via EPCAM in HCC.PMID 35150083Read ↗

Multi-omics Analysis of Microenvironment Characteristics and Immune Escape Mechanisms of Hepatocellular CarcinomaSemantic proximity Read ↗

Development and validation of a TP53-associated immune prognostic model for hepatocellular carcinomaSemantic proximity Read ↗

Development and validation of a robust immune-related risk signature for hepatocellular carcinoma.Semantic proximity Read ↗

Development and validation of a novel immune-related prognostic model in hepatocellular carcinomaSemantic proximity Read ↗

Development and validation of a robust immune-related risk signature for hepatocellular carcinomaSemantic proximity Read ↗

Identification and validation of an immune-related prognostic signature for hepatocellular carcinomaSemantic proximity Read ↗

Identification and Validation of a Tumor Microenvironment-Related Gene Signature in Hepatocellular Carcinoma PrognosisSemantic proximity Read ↗

Identification of Biomarkers of Hepatocellular Carcinoma Gene Prognosis Based on Immune-Related lncRNA Signature of Transcriptome DataSemantic proximity Read ↗

An Immune-Related Gene Signature for Predicting Survival and Immunotherapy Efficacy in Hepatocellular CarcinomaSemantic proximity Read ↗

Multi-omic analyses of hepatocellular carcinoma to determine immunological characteristics and key nodes in gene-expression network.Semantic proximity Read ↗

A Novel Immune‑Related Gene-Based Model: Prognosis and Immunotherapy Response in Hepatocellular CarcinomaSemantic proximity Read ↗

The immune-related gene-based prognostic index predicts the prognosis and effect of immune checkpoint inhibitors in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.